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Dth

SKU: orb2813978

Description

Dth is a bifunctional PROTAC molecule that combines the fluorescent RNA ligand DFHBI with the cereblon-binding moiety thalidomide. It enables targeted protein degradation studies and is used in live-cell imaging and RNA-protein interaction research in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

MW593.58
FormulaC30H29F2N5O6
SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCN(C(C)=N/C4=C\C5=CC(F)=C(O)C(F)=C5)C4=O)=O
TargetNF-κB,PROTACs,Early 2 Factor (E2F)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

Dth (orb2813978)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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