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DS69910557

SKU: orb1744409

Description

DS69910557, a potent, selective, and orally active antagonist of the human parathyroid hormone receptor 1 (hPTHR1), exhibits antagonistic activity with an IC50 value of 0.08 μM. It is useful in researching hyperparathyroidism, hypercalcemia of malignancy, and osteoporosis.

Research Area

Metabolism Research

Images & Validation

Key Properties

MW611.53
FormulaC32H33Cl2FN4O3
SMILESCC1(C(N(C2=C(C3=C1N=CC(Cl)=C3)C=CC(Cl)=C2)C4=CC=C(C=C4)N5CC(CN[C@H]6CC[C@@H](CC6)C(O)=O)(C5)F)=O)C
TargetOthers,Thyroid hormone receptor(THR)

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

DS69910557 (orb1744409)

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