DRX-065

SKU: orb1986939

Description

DRX-065 is a deuterated and stabilized R-enantiomer of pioglitazone designed for NASH research. It retains beneficial pharmacological actions—modulating mitochondrial function, exerting anti-inflammatory effects, and improving glucose metabolism—while avoiding the PPARγ-mediated weight gain associated with the parent compound. This profile supports its utility in both in vitro mechanistic studies and in vivo models of metabolic liver disease.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1259828-75-5
• MW: 357.45
• Formula: C₁₉H₂₀N₂O₃S
• SMILES: C([C@@]1(C(=O)NC(=O)S1)[2H])C2=CC=C(OCCC3=CC=C(CC)C=N3)C=C2
• Target: Endogenous Metabolite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

49835993