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Catalog Number | orb1300731 |
---|---|
Category | Small Molecules |
Description | Droxinostat |
CAS Number | 99873-43-5 |
Purity | 99.76% |
MW | 243.69 |
SMILES | CC1=CC(Cl)=CC=C1OCCCC(=O)NO |
Formula | C11H14ClNO3 |
Biological Activity | Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
99873-43-5 |
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