Doxifluridine (Standard)

SKU: orb3141437

Description

Doxifluridine (Standard) is a reference standard for research and analysis in studies involving Doxifluridine. Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity. Doxifluridine, designed to circumvent the rapid degradation of 5-FU by dihydropyrimidine dehydrogenase in the gut wall, is converted into 5-FU in the presence of pyrimidine nucleoside phosphorylase. 5-FU interferes with DNA synthesis and subsequent cell division by reducing normal thymidine production and interferes with RNA transcription by competing with uridine triphosphate for incorporation into the RNA strand.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3094-09-5
• MW: 246.19
• Formula: C₉H₁₁FN₂O₅
• SMILES: O[C@H]1[C@@H](O[C@H](C)[C@H]1O)N2C(=O)NC(=O)C(F)=C2
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others