Donepezil-d5 hydrochloride

SKU: orb3138152

Description

Donepezil-d5(hydrochloride) is the deuterated form of Donepezil (Hydrochloride). Donepezil Hydrochloride (E2020) acts as a reversible and selective inhibitor of acetylcholinesterase (AChE), with an IC50 of 6.7 nM. It demonstrates higher selectivity for AChE over butyrylcholinesterase (BuChE) and provides neuroprotective effects against Aβ42 neurotoxicity.

Images & Validation

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Key Properties

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CAS Number	1883548-90-0
MW	420.98
Formula	C₂₄H₃₀ClNO₃
SMILES	O=C1C=2C(=CC(OC)=C(OC)C2)CC1CC3CCN(CC4=C(C(=C(C(=C4[2H])[2H])[2H])[2H])[2H])CC3.Cl
Target	Cholinesterase (ChE)

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Cholinesterase (ChE)

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