DNQX Disodium

SKU: orb1220149

Description

DNQX Disodium is a water-soluble form of selective antagonist of non-NMDA receptor.

Key Properties

• CAS Number: 1312992-24-7
• MW: 296.1
• Purity: >98% (HPLC)
• Formula: C₈H₂N₄Na₂O₆
• SMILES: [Na+].[Na+].[O-]c1nc2cc(c(cc2nc1[O-])[N+]([O-])=O)[N+]([O-])=O
• Target: non-NMDA

Bioactivity

• In Vivo:
  DNQX (FG 9041), a specific AMPA receptor antagonist, given as either a 5 mg/kg or 10 mg/kg intraperitoneal dose or into the lateral cerebral ventricle (5 μl of 0.5 mg/ml) significantly diminishes phencyclidine (PCP) (40 mg/kg) and ketamine (80, 100, 120 mg/kg) hsp70 induction in the posterior cingulate and retrosplenial cortex.
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• In Vitro:
  DNQX (FG 9041) disodium salt selectively depolarizes thalamic reticular nucleus (TRN) neurons.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

non-NMDA