DNDS

SKU: orb1306687

Description

DNDS is a selective inhibitor of the voltage-gated cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel. It is widely used as a pharmacological tool in both in vitro and in vivo research to investigate CFTR function and related epithelial transport physiology.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3709-43-1
• MW: 474.33
• Purity: 99.88%
• Formula: C₁₄H₈N₂Na₂O₁₀S₂
• SMILES: [Na+].[Na+].[O-][N+](=O)c1ccc(C=Cc2ccc(cc2S([O-])(=O)=O)[N+]([O-])=O)c(c1)S([O-])(=O)=O
• Target: Others,CFTR
• Solubility: DMSO:55 mg/mL (115.95 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DNDS, CFTR

Compound Identifiers

PubChem CID

19458