DNA-PK-IN-8

SKU: orb1688209

Description

DNA-PK-IN-8 is a highly potent and selective oral inhibitor of DNA-PK with an IC50 of 0.8 nM. It exhibits synergistic anticancer activity in vitro across multiple cell lines and has shown efficacy in reducing HL-60 tumor growth in vivo when used in combination with doxorubicin.

Research Area

Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2823369-81-7
• MW: 394.43
• Formula: C₁₉H₂₂N₈O₂
• SMILES: CN1C=2C(N(CC1=O)C3CCOCC3)=NC(NC4=CN5C(C=C4C)=NC=N5)=NC2
• Target: Others,DNA-PK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163409152