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DMNB

SKU: orb1298757

Description

DMNB (6-Nitroveratraldehyde) is a small molecule inhibitor of DNA-dependent protein kinase (DNA-PK), a key enzyme in the non-homologous end-joining (NHEJ) DNA repair pathway, with an IC50 of 15 µM. It is used in research to study DSB repair mechanisms and to sensitize cells to DNA-damaging agents in both in vitro and in vivo models.

Research Area

Molecular Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number20357-25-9
MW211.17
Purity97.87% (May vary between batches)
FormulaC9H9NO5
SMILESCOC1=C(OC)C=C(C(C=O)=C1)[N+]([O-])=O
TargetDNA-PK,Others
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.47 mM);DMSO:22.5 mg/mL (106.55 mM)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, 6-Nitroveratraldehyde, dopaminergic systems, DMNB, DNA-PK, DNAPK, precursor, PET

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

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1 ml x 10 mM (in DMSO)
$ 70.00
200 mg
$ 70.00
DispatchUsually dispatched within 3-5 working days
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