DMCM hydrochloride

SKU: orb1709854

Description

DMCM hydrochloride

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1215833-62-7
• MW: 350.8
• Purity: 99.56%
• Formula: C₁₇H₁₉ClN₂O₄
• SMILES: Cl.CCc1c(ncc2[nH]c3cc(OC)c(OC)cc3c12)C(=O)OC
• Target: GABA Receptor
• Solubility: H2O:22.5 mg/mL (64.14 mM);DMSO:9 mg/mL (25.66 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.85 mM)

Bioactivity

• Target IC50:
  GABAA α5 receptor:2.2 nM (ki)|GABAA α1 receptor:ki:10 nM |GABAA α3 receptor:7.5 nM (ki)|GABAA α2 receptor:13 nM (ki)
• In Vivo:
  DMCM exhibits potent convulsant, proconvulsant, and anxiogenic properties in vivo. At doses of 20-60 mg/kg (i.p.), DMCM induces modest anxiolytic-like effects in γ2I77 mice.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

GABA Receptor, GABAA α5 receptor, GABAA, GABAA α1 receptor, GABAA α2 receptor, GABAA α3 receptor, GABAReceptor, DMCM hydrochloride, DMCM Hydrochloride

Compound Identifiers

PubChem CID

45261899