Dimethyl-SGD-1882

SKU: orb1992882

Description

Dimethyl-SGD-1882 is a potent DNA alkylating agent derived from a pyrrolobenzodiazepine (PBD) dimer. It functions as a cytotoxic payload in antibody-drug conjugates (ADCs), disrupting DNA replication in target cells. Its mechanism is studied in both in vitro cytotoxicity assays and in vivo xenograft models for oncology research.

Key Properties

• CAS Number: 3026416-27-0
• MW: 753.84
• Formula: C₄₄H₄₃N₅O₇
• SMILES: C[C@@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@]6(C)N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(N)C=C8)C1
• Target: ADC Cytotoxin,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145712366