DHODH-IN-25

SKU: orb2566494

Description

DHODH-IN-25 (Compound 25) is a potent, orally bioavailable dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 5.4 nM against the human enzyme. It is a valuable research tool for studying acute myeloid leukemia (AML), with utility in both in vitro cellular assays and in vivo preclinical models.

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 2619531-95-0
• MW: 535.85
• Formula: C₂₂H₁₉ClF₅N₃O₅
• SMILES: O([C@H](C(F)(F)F)C)C1=C(C(NC2=C(Cl)C=CC=C2F)=O)C=C(F)C(NC(=O)N3C(CO)CCC3=O)=C1
• Target: DNA/RNA Synthesis,Dehydrogenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156128024