DHODH-IN-13

SKU: orb1709882

Description

DHODH-IN-13 is a small molecule inhibitor of dihydroorotate dehydrogenase (DHODH) exhibiting an IC50 of 4.3 μM against the rat liver enzyme. It serves as a research tool for investigating rheumatoid arthritis, with applications in both in vitro enzymatic assays and in vivo disease model studies.

Research Area

Cell Biology, Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 1364791-86-5
• MW: 273.17
• Purity: 99.66% (May vary between batches)
• Formula: C₁₀H₆F₃N₃O₃
• SMILES: C(NC1=CC=C(C(F)(F)F)C=C1)(=O)C=2C(=O)NON2
• Target: DNA/RNA Synthesis,Dehydrogenase
• Solubility: DMSO:50 mg/mL (183.04 mM)

Bioactivity

• Target IC50:
  DHODH (rat liver):4.3 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DHODH IN 13, DHODHIN13, DHODH-IN-13, DHODH, Rat liver DHODH

Compound Identifiers

PubChem CID

57381308