DHFR-IN-8

SKU: orb2277726

Description

DHFR-IN-8 (compound 6r) is a potent dihydrofolate reductase (DHFR) inhibitor that blocks essential nucleotide synthesis, thereby inhibiting bacterial growth. It demonstrates potent anti-MRSA activity, with an IC50 of 15.6 ng/mL against strain ATCC 43300, and has shown efficacy in murine systemic and thigh infection models.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Key Properties

• MW: 346.41
• Formula: C₁₈H₁₄N₆S
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others