DHFR-IN-4

SKU: orb1688549

Description

DHFR-IN-4

Research Area

Cardiovascular Research, Cell Biology, Metabolism Research, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2820126-49-4
• MW: 371.46
• Purity: 99.41% (May vary between batches)
• Formula: C₁₈H₂₁N₅O₂S
• SMILES: O=C(NN)C1=CSC2=NC(=C(C=3C=CC(=CC3)C)N21)CN4CCOCC4
• Target: DHFR,EGFR

Bioactivity

• Target IC50:
  EGFR:246 nM|DHFR:123 nM|HER2:357 nM
• In Vitro:
  Remarkable broad-spectrum cytotoxic potency against HepG2, MCF-7, HCT-116, PC3, and HeLa is shown by DHFR-IN-4 (compound 42) at concentrations ranging from 0 to 100 μM over a 72-hour period.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DHFR

Compound Identifiers

PubChem CID

165412710