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DHFR-IN-20

SKU: orb2665164

Description

DHFR-IN-20 (LA1) is a potent and selective dihydrofolate reductase (DHFR) inhibitor targeting Plasmodium falciparum. It demonstrates sub-nanomolar inhibition against wild-type and quadruple-mutant PfDHFR with significant selectivity over the human enzyme. This compound is a valuable chemical tool for antimalarial drug discovery research in biochemical and cellular assays.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology

Images & Validation

Key Properties

TargetParasite,DHFR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

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Protocol Information