DFPQ

• Catalog Number: orb2564724
• Category: Small Molecules
• Description: DFPQ is a powerful and selective β-arrestin-biased negative allosteric modulator(NAM) targeting the β2-adrenergic receptor. It specifically inhibits the interaction of β-arrestin with β2AR without altering β-agonist-induced cAMP production. Additionally, DFPQ reduces functional desensitization of the β2AR in airway smooth muscle, enhancing β-agonists' capacity to maintain bronchorelaxation and curbing cell migration during prolonged β-agonist treatment.
• Purity: 98.00%
• MW: 354.40
• CAS Number: 911678-60-9
• Formula: C₂₀H₂₀F₂N₄
• SMILES: FC1=CC=C(C=C1F)NC=2N=C3C=CC=CC3=C(N2)NC4CCCCC4
• Storage: -20°C
• Note: For research use only