DETD-35

SKU: orb2663556

Description

DETD-35 is a multi-targeted small molecule inhibitor that suppresses MEK-ERK, Akt, and STAT3 signaling, promoting apoptosis and overcoming Vemurafenib resistance in melanoma cells. With potent activity across multiple cell lines (IC50 2.5-6.0 µM), it is a valuable tool for in vitro studies of targeted therapy and drug resistance mechanisms in melanoma research.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1836209-98-3
• MW: 444.48
• Formula: C₂₇H₂₄O₆
• SMILES: C\C1=C\[C@@H](OC(=O)CC2=C3C=CC=CC3=CC=C2)[C@H]2[C@H](CC3=C[C@@H](C1)OC3=O)OC(=O)C2=C
• Target: Akt|||Apoptosis|||ERK|||STAT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176419152