Desthiobiotin-Iodoacetamide

SKU: orb2279060

Description

Desthiobiotin-Iodoacetamide is a chemical probe designed for labeling reactive cysteine residues in proteins. It is used in proteomics for studying cysteine reactivity and protein function in vitro, and its desthiobiotin tag enables gentle streptavidin-based purification. This reagent also has potential applications as a cleavable linker in antibody-drug conjugate (ADC) research.

Key Properties

• CAS Number: 2924824-04-2
• MW: 424.28
• Purity: 99.35% (May vary between batches)
• Formula: C₁₄H₂₅IN₄O₃
• SMILES: C(CCCCC(NCCNC(CI)=O)=O)[C@@H]1[C@H](C)NC(=O)N1
• Target: ADC Linker
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.36 mM);DMSO:40 mg/mL (94.28 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ADCLinker

Quick Database Links

Gene Symbol

ADC Linker