Deslanoside

SKU: orb1299144

Description

Deslanoside is a fast-acting cardiac glycoside used in research on congestive heart failure and supraventricular arrhythmias. It functions by inhibiting Na-K-ATPase, elevating intracellular sodium and calcium. This mechanism is studied in both in vitro assays and in vivo models of cardiac function.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 17598-65-1
• MW: 943.08
• Purity: 99.89%
• Formula: C₄₇H₇₄O₁₉
• SMILES: [H][C@@]1(C[C@H](O)[C@H](O[C@@]2([H])C[C@H](O)[C@H](O[C@@]3([H])C[C@H](O)[C@H](O[C@]4([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]1CC[C@@]2(C)[C@]([H])(CC[C@]3([H])[C@]2([H])C[C@@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1
• Target: ATPase,Drug Metabolite
• Solubility: DMSO:95 mg/mL (100.73 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.5 mM)

Bioactivity

• In Vitro:
  Deslanoside increases forearm blood flow and cardiac index and decreased heart rate concomitant with a marked decrease in skeletal muscle sympathetic nerve activity . Deslanoside is a metabolite of Lanatoside C .

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

rate, supraventricular, Sodium potassium pump, DrugMetabolite, Drug Metabolite, Desacetyllanatoside C, Deslanoside, cardiac, arrhythmias, glycoside, failure, Deacetyllanatoside C, Inhibitor, heart, Na+/K+-ATPase, Na+/K+ ATPase, inhibit

Compound Identifiers

PubChem CID

28620