α-Demethylnaproxen

SKU: orb1299615

Description

α-Demethylnaproxen is a competitive inhibitor of cyclooxygenase (COX) enzymes, with Ki values of 21 µM for COX-1 and 19 µM for COX-2. This small molecule is used in biochemical research to study COX inhibition mechanisms and inflammatory pathways in vitro.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience

Key Properties

• CAS Number: 23981-47-7
• MW: 216.23
• Purity: 97.57% (May vary between batches)
• Formula: C₁₃H₁₂O₃
• SMILES: COc1ccc2cc(CC(O)=O)ccc2c1
• Target: Drug Metabolite,COX
• Solubility: DMSO:3.6 mg/mL (16.65 mM)

Bioactivity

• Target IC50:
  COX-2:19 μM(ki)|COX-1:21 Μm(ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX, alpha-Demethylnaproxen, 6methoxy Naphthalene Acetic Acid, a-Demethylnaproxen, 6 methoxy Naphthalene Acetic Acid, α-Demethylnaproxen

Compound Identifiers

PubChem CID

32176