Delpazolid

SKU: orb1303098

Description

Delpazolid (LCB01-0371) is a novel cyclic amidrazone oxazolidinone antibiotic demonstrating potent in vitro activity against Gram-positive clinical isolates and superior in vivo efficacy compared to linezolid in murine systemic infection models, exhibiting bacteriostatic action against Staphylococcus aureus.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 1219707-39-7
• MW: 308.31
• Purity: 99.62% (May vary between batches)
• Formula: C₁₄H₁₇FN₄O₃
• SMILES: CN1CCN(C=N1)c1ccc(cc1F)N1C[C@H](CO)OC1=O
• Target: Antibiotic,Antibacterial
• Solubility: DMSO:13 mg/mL (42.17 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.49 mM)

Bioactivity

• Target IC50:
  MRSA:2 μg/mL (MIC90)|MSSA:2 μg/mL (MIC90)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, Antibiotic, Antibacterial, Delpazolid, Inhibitor, LCB01-0371, inhibit

Compound Identifiers

PubChem CID

44205191