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Catalog Number | orb1685929 |
---|---|
Category | Small Molecules |
Description | Debio 0617B |
CAS Number | 1332329-27-7 |
Purity | 98% |
MW | 581.98 |
SMILES | ClC=1C(N2CC=3C(CC2)=NC(NC4=CC=C(C(NC)=O)C=C4)=NC3)=CC(NC(=O)C5=CC(C(F)(F)F)=CC=N5)=CC1 |
Formula | C28H23ClF3N7O2 |
Biological Activity | Debio 0617B is a multi-kinase inhibitor that reduces maintenance and self-renewal of primary human AML CD34+ stem/progenitor cells. debio 0617B targets key kinases upstream of STAT3/STAT5 signalling, such as JAK, ABL, SRC and class III/V receptor tyrosine kinases. debio 0617B can be used to study STAT3 driven solid tumours. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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