ddUTP

• Catalog Number: orb2277838
• Category: Small Molecules
• Description: ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) is a selective inhibitor of HIV and AMV reverse transcriptases, with Ki values of 0.05 µM for HIV and 1 µM for AMV. It is preferentially incorporated at dTTP sites within the DNA strand, thereby preventing further chain elongation [1].
• CAS Number: 84445-38-5
• Purity: 98.00%
• MW: 448.111
• SMILES: [O-]P([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@@H]1CC[C@@H](O1)n1ccc(=O)[nH]c1=O
• Formula: C₉H₁₅N₂O₁₃P₃
• Biological Activity: ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) serves as a selective inhibitor of HIV and AMV reverse transcriptases with Ki values of 0.05 µM for HIV and 1 µM for AMV, respectively. This compound is preferentially incorporated at dTTP sites within the DNA strand, thereby preventing further chain elongation [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.