DDRI-18

SKU: orb1703522

Description

DDRI-18 is a novel small molecule that disrupts the DNA damage response by inhibiting non-homologous end joining (NHEJ). It acts as a chemosensitizer, enhancing the cytotoxicity of DNA-damaging agents in cancer research, with demonstrated efficacy in both in vitro and in vivo experimental models.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 4402-18-0
• MW: 416.48
• Formula: C₂₆H₂₀N₆
• SMILES: NC=1C=C(C=2NC=3C(N2)=CC=C(C3)C=4C=C5C(=CC4)N=C(N5)C6=CC(N)=CC=C6)C=CC1
• Target: DNA/RNA Synthesis
• Solubility: DMSO:20 mg/mL (48.02 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DDRI18, DDRI-18, DDRI 18, DNA/RNA Synthesis, DNA Synthesis, DNASynthesis, RNASynthesis, RNA Synthesis

Compound Identifiers

PubChem CID

4644404