(d(CH2)51,Tyr(Me)2,Arg8)-Vasopressin

SKU: orb1679215

Description

This small molecule is a potent and selective antagonist of the vasopressin V1A receptor, blocking vasopressin and oxytocin signaling in vitro (IC50 = 5 nM and 30 nM, respectively). In vivo, it produces sustained antivasopressor effects and demonstrates region-specific anxiolytic activity within the dorsal hippocampus, making it a valuable research tool for neuroendocrinology and behavioral studies.

Research Area

Metabolism Research; Pharmacology & Drug Discovery

Key Properties

• Target: Vasopressin Receptor
• CAS Number: 73168-24-8
• MW: 1151.38
• Formula: C₅₂H₇₄N₁₄O₁₂S₂
• SMILES: O=C1CC2(SSC[C@@H](C(=O)N3[C@H](C(N[C@H](C(NCC(N)=O)=O)CCCNC(=N)N)=O)CCC3)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CC=C(OC)C=C5)N1)CCCCC2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

9833460