DC10SMe

SKU: orb1992895

Description

DC10SMe is a potent DNA alkylating agent utilized in the construction of antibody-drug conjugates (ADCs). It demonstrates high cytotoxicity in vitro, with IC50 values of 15 pM, 12 pM, and 12 pM against Ramos, Namalwa, and HL60/s cancer cell lines, respectively. This compound is a valuable tool for targeted cancer therapy research.

Research Area

Molecular Biology

Key Properties

• MW: 647.77
• Formula: C₃₅H₂₉N₅O₄S₂
• SMILES: O=C(C1=CC2=C(C=CC(NC(CCSSC)=O)=C2)N1)NC3=CC4=C(C=C3)NC(C(N5C(C67[C@H](C7)C5)=CC(C8=C6C=CC=C8)=O)=O)=C4
• Target: ADC Cytotoxin,DNA Alkylator/Crosslinker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

56951502