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DC10SMe

SKU: orb1992895

Description

DC10SMe is a potent DNA alkylating agent utilized in the construction of antibody-drug conjugates (ADCs). It demonstrates high cytotoxicity in vitro, with IC50 values of 15 pM, 12 pM, and 12 pM against Ramos, Namalwa, and HL60/s cancer cell lines, respectively. This compound is a valuable tool for targeted cancer therapy research.

Research Area

Molecular Biology

Images & Validation

Key Properties

MW647.77
FormulaC35H29N5O4S2
SMILESO=C(C1=CC2=C(C=CC(NC(CCSSC)=O)=C2)N1)NC3=CC4=C(C=C3)NC(C(N5C(C67[C@H](C7)C5)=CC(C8=C6C=CC=C8)=O)=O)=C4
TargetADC Cytotoxin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information