DBCO-PEG4-Maleimide

SKU: orb2279268

Description

DBCO-PEG4-Maleimide is a non-cleavable, heterobifunctional linker for constructing bioconjugates like ADCs. Its DBCO group enables copper-free click chemistry with azides, while the maleimide reacts with thiols. This reagent is widely used for in vitro and in vivo labeling, bioorthogonal ligation, and targeted drug delivery research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1480516-75-3
• MW: 674.74
• Purity: 98.00% (May vary between batches)
• Formula: C₃₆H₄₂N₄O₉
• SMILES: O=C1C=CC(=O)N1CCC(=O)NCCOCCOCCOCCOCCC(=O)NCCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2
• Target: ADC Linker,PROTAC Linker
• Solubility: DMSO:40 mg/mL (59.28 mM)

Bioactivity

• In Vitro:
  ADCs consist of an antibody linked to an ADC cytotoxin via an ADC linker.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DBCOPEG4Maleimide, DBCO-PEG-4-Maleimide, DBCO-PEG4-Maleimide, DBCO PEG4 Maleimide, ADCLinker, ADC Linker, Cleavable

Compound Identifiers

PubChem CID

86580488