DBCO-Biotin

SKU: orb1909235

Description

DBCO-Biotin is an alkyl chain-based linker used in the construction of PROTACs and other bifunctional molecules. It enables bioorthogonal conjugation via its DBCO moiety and subsequent detection or purification through biotin-streptavidin interaction, facilitating both in vitro and in vivo target engagement studies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1418217-95-4
• MW: 502.63
• Formula: C₂₈H₃₀N₄O₃S
• SMILES: C(CCNC(CCCC[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H])=O)(=O)N3C=4C(C#CC=5C(C3)=CC=CC5)=CC=CC4
• Target: PROTAC Linker

Storage & Handling

• Storage: store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Azadibenzocyclooctyne-Biotin conjugate, Alkyl-Chain, DBCO-Biotin, PROTAC Linker, PROTACLinker

Compound Identifiers

PubChem CID

121235600