DB008

SKU: orb1744085

Description

DB008 is a potent, selective, and cell-permeable PARP16 inhibitor with an IC50 of 0.27 µM, featuring an acrylamide warhead for covalent engagement. This tool compound enables the study of PARP16's roles in cellular stress responses, such as the unfolded protein response, in both in vitro and cellular research contexts.

Research Area

Epigenetics & Chromatin, Molecular Biology

Key Properties

• MW: 444.46
• Formula: C₂₅H₂₁FN₄O₃
• SMILES: C=CC(=O)N1CCN(CC1)C(=O)C2=C(C=CC(=C2)CC3=NNC(=O)C4=C3C=C(C=C4)C#C)F
• Target: PARP,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166642566