Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Darexaban

SKU: orb1304515

Description

Darexaban (YM-150) is a selective, competitive direct Factor Xa inhibitor. Its active metabolite further suppresses thrombin generation at thrombus sites, demonstrating dose-dependent antithrombotic effects in research models for venous and arterial thrombosis.

Research Area

Metabolism Research, Protein Biochemistry

Images & Validation

Key Properties

CAS Number365462-23-3
MW474.55
Purity98.33% (May vary between batches)
FormulaC27H30N4O4
SMILESCOc1ccc(cc1)C(=O)Nc1cccc(O)c1NC(=O)c1ccc(cc1)N1CCCN(C)CC1
TargetFactor Xa,Serine Protease
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.54 mM);DMSO:245 mg/mL (516.28 mM)

Bioactivity

Target IC50
FXa:54.6 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Darexaban, Tanexaban, Darexaban, antithrombotic, anticoagulant, oral, inhibit, Inhibitor, Factor Xa, FactorXa, Fxa, YM150, YM-150, YM 150, prothrombin, Threonine proteases, Serine endopeptidases, Ser/Thr Protease, Serine proteases, time

Similar Products

  • Darexaban glucuronide [orb1700769]

    432029-12-4

    650.68

    C33H38N4O10

    50 mg, 100 mg, 25 mg
  • Darexaban maleate [orb1740127]

    365462-24-4

    590.63

    C31H34N4O8

    50 mg, 100 mg, 25 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

Darexaban (orb1304515)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 130.00
1 ml x 10 mM (in DMSO)
$ 140.00
10 mg
$ 190.00
25 mg
$ 290.00
50 mg
$ 420.00
100 mg
$ 580.00
200 mg
$ 810.00
DispatchUsually dispatched within 3-5 working days
Bulk Enquiry