Dalvastatin

SKU: orb1702385

Description

Dalvastatin (RG-12561) is an orally bioavailable HMG-CoA reductase inhibitor that lowers cholesterol synthesis. It competitively inhibits rat hepatic HMG-CoA reductase with an IC50 of 3.4 nM and shows an ED50 of 0.9 mg/kg for inhibiting cholesterol biosynthesis in rat liver sections in vivo.

Research Area

Metabolism Research

Key Properties

• CAS Number: 132100-55-1
• MW: 386.5
• Purity: 98.80%
• Formula: C₂₄H₃₁FO₃
• SMILES: C(=C/[C@H]1C[C@H](O)CC(=O)O1)\C2=C(CC(C)(C)CC2(C)C)C3=CC(C)=C(F)C=C3
• Target: HMG-CoA Reductase
• Solubility: DMSO:50 mg/mL (129.37 mM)

Storage & Handling

• Storage: store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Dalvastatin, HMGCoA Reductase, HMG-CoA Reductase (HMGCR), HMGCoAReductase, RG12561, RG-12561, RG 12561

Compound Identifiers

PubChem CID

6436002