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D1R antagonist 2

SKU: orb3173032

Description

D1R antagonist 2 (Compound 13a) is a blood-brain barrier-permeable D1R antagonist, with IC50 values of 35.6 nM for cAMP-based D1R and 70 nM for β-arrestin-based D1R. It effectively inhibits D1R-mediated cAMP and β-arrestin recruitment and is applicable in studies of neurodegenerative and neuropsychiatric disorders, such as schizophrenia, Parkinson's disease, and Alzheimer's disease.

Images & Validation

Key Properties

TargetArrestin,Dopamine Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information