(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)

SKU: orb1980840

Description

This synthetic peptide is a potent corticotropin-releasing factor (CRF) receptor antagonist. It is a valuable research tool for studying neuroendocrine interactions, particularly in countering interleukin-1α-mediated suppression of luteinizing hormone secretion in both in vitro and in vivo models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Target: CRFR
• CAS Number: 150646-45-0
• MW: 3553.12
• Formula: C₁₅₉H₂₆₇N₄₉O₄₃
• SMILES: [C@H](CC1=CN=CN1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(N)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCC)=O)(CC(C)C)C)=O)CCCCN)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CO)=O)=O)C)=O)CCC(N)=O)=O)CCC(N)=O)=O)C)=O)CC(C)C)=O)CCC(N)=O)=O)CCC(O)=O)=O)C)=O)CCCNC(=N)N)=O)C)=O)CCCC)=O)CCC(O)=O)=O)CC(C)C)=O)[C@@H](C)C)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(C)C)=O)NC([C@@H](CC3=CC=CC=C3)N)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652864