D-Luciferin

SKU: orb1304335

Description

D-Luciferin is the natural substrate for firefly luciferase, enabling bioluminescence through the emission of yellow-green light (~560 nm). It is widely employed in both in vitro luciferase assays and in vivo bioluminescence imaging for applications in molecular biology, oncology, and drug discovery research.

Key Properties

• CAS Number: 2591-17-5
• MW: 280.32
• Purity: 99.83% (May vary between batches)
• Formula: C₁₁H₈N₂O₃S₂
• SMILES: OC(=O)[C@H]1CS\C(N1)=c1\nc2C=CC(=O)C=c2s1
• Target: Others
• Solubility: 10% DMSO+90% Saline:5.5 mg/mL (19.62 mM);Ethanol:1 mg/mL (3.57 mM);DMSO:55 mg/mL (196.2 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5.5 mg/mL (19.62 mM)

Bioactivity

• In Vivo:
  In an immunocompetent mouse model of ovarian cancer, use of D-luciferin substrate and firefly luciferase preserves tumor-host immune interactions, since bioluminescent imaging is a more sensitive indication of tumor growth than weight gain.
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• In Vitro:
  D-luciferin reacts with luciferase, ATP and oxygen with light emission, and the light is detected by a sensitive photographic film, thereby permitting the visualization of the alkaline phosphatase-conjugated antibodies.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DLuciferin, D-Luciferin, D Luciferin, D-(-)-Luciferin, Beetle Luciferin, inhibit, Inhibitor, Firefly luciferin

Compound Identifiers

PubChem CID

92934