D-Galactosamine HCl

SKU: orb1220306

Description

D-Galactosamine HCl hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.

Key Properties

• CAS Number: 1772-03-8
• MW: 215.63
• Purity: >98% (HPLC)
• Formula: C₆H₁₄ClNO₅
• SMILES: Cl.N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O
• Target: Others
• Solubility: DMSO:25mg/ml(215.63mM)

Bioactivity

• In Vivo:
  Animal model: C57BL/6J mice. Dosage: 400 mg/kg, together with Lipopolysaccharide (HY-D1056) (LPS, 10 μg/kg). Administration: i.p. Result: Induces a model of acute liver failure, with necrosis in the liver. Increased serum ALT and AST levels and serum inflammatory cytokine concentrations, such as TNF-α, IFN-γ, IL-1β, IL-6, and IL-18.
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Others