D-(-)-3-Phosphoglyceric acid disodium

SKU: orb1693087

Description

D-(-)-3-Phosphoglyceric acid disodium salt is a key metabolic intermediate in glycolysis, gluconeogenesis, and amino acid biosynthesis. It serves as a valuable research tool for studying enzymatic mechanisms, such as the competitive inhibition of yeast enolase, in both in vitro and cellular assays.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 80731-10-8
• MW: 230.02
• Purity: 93.00% (May vary between batches)
• Formula: C₃H₅Na₂O₇P
• SMILES: C([C@H](C(=O)[O-])O)OP(=O)(O)[O-].[Na+].[Na+]
• Target: MDM-2/p53,Glucokinase,Dehydrogenase,Apoptosis,Others
• Solubility: PBS (pH 7.2):10 mg/mL (43.47 mM);H2O:242.5 mg/mL (1054.26 mM)

Bioactivity

• In Vitro:
  D-(-)-3-Phosphoglyceric acid disodium competitively inhibits yeast enolase. The enzyme-Mg2+ complex was thermally titrated with 3-phosphoglyceric acid.The heat absorbed when 3-phosphoglyceric acid binds to enolase has been measured in Tris, in Hepes, and in Pipes at the same enzyme, metal, and inhibitor concentrations.
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

3-Phospho-D-glyceric acid, 3-Phospho-D-glyceric acid disodium, D-3-Phosphoglyceric acid, D-3-Phosphoglyceric acid disodium

Compound Identifiers

PubChem CID

16219906