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Catalog Number | orb1303563 |
---|---|
Category | Small Molecules |
Description | CZC-54252 hydrochloride |
CAS Number | 1784253-05-9 |
Purity | 98.21% |
MW | 541.45 |
SMILES | Cl.O=S(=O)(NC=1C=CC=CC1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCOCC4)C |
Formula | C22H26Cl2N6O4S |
Biological Activity | CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human neuronal injury with an EC50 of 1 nM. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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