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Cytarabine triphosphate

SKU: orb1691822

Description

Cytarabine triphosphate (Ara-CTP) is the active metabolite of Cytarabine and acts as a competitive inhibitor of DNA synthesis. Its intracellular concentration serves as a predictive biomarker for the chemosensitivity of leukemic blasts to Cytarabine in both in vitro and in vivo research models for acute myeloid leukemia.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number13191-15-6
MW483.16
FormulaC9H16N3O14P3
SMILESNc1ccn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@@H]2O)c(=O)n1
TargetOthers,DNA/RNA Synthesis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Cytarabine triphosphate (orb1691822)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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