Cytarabine 5′-monophosphate

SKU: orb2283326

Description

Cytarabine 5′-monophosphate (ara-CMP) is the active phosphorylated metabolite of the antimetabolite cytarabine. It functions by incorporating into DNA via DNA polymerase α, thereby inhibiting DNA replication. This mechanism has demonstrated efficacy in research models, including the inhibition of yeast replication in vitro and improved survival in murine leukemia studies in vivo.

Research Area

Cell Biology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 7075-11-8
• MW: 323.198
• Formula: C₉H₁₄N₃O₈P
• SMILES: Nc1ccn([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@@H]2O)c(=O)n1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

65177