Cyclosporin B

• Catalog Number: orb1705942
• Category: Small Molecules
• Description: Cyclosporin B
• CAS Number: 63775-95-1
• Purity: 98%
• MW: 1188.58
• SMILES: C\C=C\C[C@@H](C)[C@@H](O)[C@@H]1N(C)C(=O)C(C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](C)NC1=O)C(C)C
• Formula: C₆₁H₁₀₉N₁₁O₁₂
• Biological Activity: Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B into hepatocytes. Cyclosporin B also inhibits RANKL-induced TRAP phosphatase activity, inducing apoptosis in osteoclasts. Cyclosporin B is a derivative of cyclosporin A that exhibits significantly less immunosuppressive activity.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.