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CTCE-9908

SKU: orb1679302

Description

This small molecule CXCR4 antagonist triggers mitotic catastrophe in ovarian cancer cells in vitro. It demonstrates additive cytotoxicity with taxol and enhances the efficacy of docetaxel in murine xenograft models, supporting its investigation in combination chemotherapy for oncology research.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetCXCR
CAS Number1030384-98-5
MW1927.27
FormulaC86H147N27O23
SMILES[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@@H](CCCCNC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCCCN)N)=O)=O)[C@H](C)C)=O)CO)=O)CC(C)C)=O)CO)=O)=O)CCCNC(=N)N)=O)C(N)=O)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCCCN)N)=O)=O)[C@@H](C)C)=O)CO)=O)CC(C)C)=O)CO)=O

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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CTCE-9908 (orb1679302)

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