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Cruzain-IN-1

SKU: orb1302606

Description

Cruzain-IN-1 (ML092) is a potent, reversible covalent inhibitor of the cysteine protease Cruzain, exhibiting an IC50 of 10 nM. It serves as a valuable biochemical tool for in vitro enzyme inhibition studies and as a lead compound in parasitology research targeting Trypanosoma cruzi, the causative agent of Chagas disease.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number1199523-24-4
MW300.27
Purity99.25% (May vary between batches)
FormulaC14H10F2N6
SMILESCCn1cnc2c(Nc3cc(F)cc(F)c3)nc(nc12)C#N
TargetAntibiotic
SolubilityDMSO:45 mg/mL (149.87 mM)

Bioactivity

Target IC50
Cruzain:10 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Cruzain IN 1, CruzainIN1, Cruzain-IN-1, Inhibitor, ML 092, ML092, ML-092, inhibit, Trypanosoma cruzi

Similar Products

  • ML092 [orb1221611]

    >98% (HPLC)

    1199523-24-4

    300.27

    C14H10F2N6

    2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 80.00
5 mg
$ 120.00
1 ml x 10 mM (in DMSO)
$ 120.00
10 mg
$ 160.00
25 mg
$ 270.00
50 mg
$ 380.00
100 mg
$ 520.00
200 mg
$ 700.00
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