Crizotinib-d5

SKU: orb2299893

Description

Crizotinib-d5 is a deuterated analog of the tyrosine kinase inhibitor Crizotinib (CAS 877399-52-5). This compound potently inhibits c-MET and ALK kinases and is widely used in biochemical and cellular assays to study targeted cancer therapies, including in preclinical models of ALK-positive non-small cell lung cancer.

Research Area

Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1395950-84-1
• MW: 455.37
• Formula: C₂₁H₁₇D₅Cl₂FN₅O
• SMILES: C1(F)C(Cl)=C([C@H](OC2C=C(C3C=NN(C4([2H])C([2H])([2H])CNCC4([2H])[2H])C=3)C=NC=2N)C)C(Cl)=CC=1
• Target: ROS Kinase,Autophagy,c-Met/HGFR,ALK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156588737