CPUY192018

SKU: orb1700809

Description

CPUY192018 is a small molecule Keap1-Nrf2 interaction inhibitor with cytoprotective properties. It has been shown in vitro to inhibit glycolysis, induce mitophagy, and enhance oxidative stress resistance in models like NCM460 colon cells, supporting research into cytoprotective pathways.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 1567836-15-0
• MW: 614.64
• Purity: 98.90%
• Formula: C₂₈H₂₆N₂O₁₀S₂
• SMILES: O=C(O)CN(C=1C=CC(=C2C=CC=CC21)N(CC(=O)O)S(=O)(=O)C3=CC=C(OC)C=C3)S(=O)(=O)C4=CC=C(OC)C=C4
• Target: Nrf2,Others,ROS,NF-κB,Apoptosis
• Solubility: DMSO:200 mg/mL (325.39 mM)

Bioactivity

• Target IC50:
  Keap1-Nrf2-ARE:0. 0.63 µM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CPUY 192018, CPUY192018, CPUY-192018, CPUY192018 Disodium, CPUY-192018 Disodium, CPUY192018 Na2, CPUY192018disodium, CPUY192018-disodium, KEAP1-Nrf2

Compound Identifiers

PubChem CID

73330369