CPT-Se4

SKU: orb1744183

Description

CPT-Se4 is a selenium-modified camptothecin derivative that potently induces apoptosis in cancer cells by disrupting redox balance, elevating ROS, and depleting glutathione. It demonstrates broad cytotoxicity in vitro against multiple cancer cell lines, including HeLa and Hep G2, with IC50 values in the low micromolar range, supporting its investigation as an antitumor agent.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 2968315-03-7
• MW: 622.39
• Formula: C₂₅H₂₄N₂O₇Se₂
• SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)OC(=O)OCC[Se][Se]CCO
• Target: Apoptosis,Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162679308