COX-2/5-LOX-IN-1

• Catalog Number: orb1688362
• Category: Small Molecules
• Description: COX-2/5-LOX-IN-1
• CAS Number: 2410384-50-6
• Purity: 98%
• MW: 383.83
• SMILES: C(O)(=O)C=1C=C(N(N1)C2=CC=C(S(N)(=O)=O)C=C2)C=3SC(Cl)=CC3
• Formula: C₁₄H₁₀ClN₃O₄S₂
• Biological Activity: COX-2/5-LOX-IN-1 (compound 3a), a benzothiophen-2-yl pyrazole carboxylic acid derivative, is a potent and dual inhibitor of COX-2 / 5-LOX. It exhibits superior analgesic and anti-inflammatory properties compared to Celecoxib and Indomethacin. COX-2/5-LOX-IN-1 displays strong inhibitory activity against COX-1, COX-2, and 5-LOX, with IC50 values of 12.13 μM, 0.4 μM, and 4.96 μM, respectively [1].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.