Rac-ZINC4085554

SKU: orb1298030

Description

Compound 1T-0219 (SC) is a cell-permeable small molecule that selectively disrupts the AKT1-FAK protein interaction. It inhibits pressure-induced FAK phosphorylation in cells like SW620 colon carcinoma, making it a useful research tool for studying mechanotransduction and cancer cell migration in vitro.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 383147-92-0
• MW: 413.38
• Purity: 90.00%
• Formula: C₂₀H₁₉N₃O₇
• SMILES: COC1=CC=C(C=C1)C(=O)O\N=C1/CCCCC1C1=C(C=C(C=C1)[N+]([O-])=O)[N+]([O-])=O
• Target: FAK,Akt
• Solubility: DMSO:5 mg/mL (12.1 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AKT1-FAK, Compound 1T 0219, Compound 1T 0219 (SC), Compound 1T0219, Compound 1T-0219, Compound 1T0219 (SC)

Compound Identifiers

PubChem CID

9638862