Colivelin

SKU: orb1296485

Description

Colivelin is a synthetic, neuroprotective hybrid peptide derived from humanin (HN) that functions as a potent STAT3 activator. It is utilized in research to study neuroprotection and neurodegenerative disease mechanisms, demonstrating efficacy in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 867021-83-8
• MW: 2645.1
• Purity: >99.99% (May vary between batches)
• Formula: C₁₁₉H₂₀₆N₃₂O₃₅
• SMILES: C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CO)=O)[C@H](CC)C)(=O)N1[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N3[C@H](C(O)=O)CCC3)CC(C)C)=O)CC(O)=O)=O)[C@H](CC)C)=O)CCC(O)=O)=O)=O)[C@@H](C)O)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)CO)=O)C)=O)=O)C)=O)CCC2)C)=O)CCC1
• Target: STAT,Beta Amyloid
• Solubility: DMSO:50 mg/mL (18.9 mM);5% DMSO+40% PEG300+5% Tween 80+50% Saline:1 mg/mL (0.38 mM);Ethanol:< 1 mg/mL (insoluble);PBS:< 1 mg/mL (Insoluble or slightly soluble)

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

β Amyloid, βAmyloid, β-amyloid peptide, STAT3, STAT, b Amyloid, Amyloid-β, brain, bAmyloid, alzheimer, Abeta, disease, Colivelin, BetaAmyloid, Beta Amyloid, Inhibitor, injury, neurological, Neuroprotectant, ischemic, inhibit

Compound Identifiers

PubChem CID

90477169